Algorithmic assessment of cellular senescence in experimental and clinical specimens
Nature, Nature Protocols, Published 28 April 2021Read more
Down-Regulation of the Proteoglycan Decorin Fills in the Tumor-Promoting Phenotype of Ionizing Radiation-Induced Senescent Human Breast Stromal Fibroblasts
PMC 2021 Apr; 13(8): 1987Read more
Hepatic Senescence Accompanies the Development of NAFLD in Non-Aged Mice Independently of Obesity
PMC 2021 Apr; 22(7): 3446.Read more
Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression
Mol Cell 2021 Mar 27;S1097-2765(21)00213-6. doi: 10.1016/j.molcel.2021.03.018.Read more
Implication of Dietary Iron-Chelating Bioactive Compounds in Molecular Mechanisms of Oxidative Stress-Induced Cell Ageing
2021 Mar; 10(3): 491. Published online 2021 Mar 21. doi: 10.3390/antiox10030491Read more
Intra-Articular Injection of (−)-Epigallocatechin 3-Gallate (EGCG) Ameliorates Cartilage Degeneration in Guinea Pigs with Spontaneous Osteoarthritis
A Novel Lipofuscin-detecting Marker of Senescence Relates With Hypoxia, Dysregulated Autophagy and With Poor Prognosis in Non-small-cell-lung Cancer
In Vivo. Nov-Dec 2020;34(6):3187-3193. doi: 10.21873/invivo.12154.Read more
The bright and dark side of skin senescence. Could skin rejuvenation anti-senescence interventions become a "bright" new strategy for the prevention of age-related skin pathologies?
Elsevier Volume 193, January 2021, 111409Read more
Improved Autophagic Flux in Escapers from Doxorubicin-Induced Senescence/Polyploidy of Breast Cancer Cells
2020 Sep; 21(17): 6084. Published online 2020 Aug 24. doi: 10.3390/ijms21176084Read more
Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation
2020; 11: 2711. Published online 2020 Jun 1. doi: 10.1038/s41467-020-16475-3
Conditioning attenuates kidney and heart injury in rats following transient suprarenal occlusion of the abdominal aorta
2020; 10: 5040. Published online 2020 Mar 19. doi: 10.1038/s41598-020-61268-9Read more
ZNF746/PARIS overexpression induces cellular senescence through FoxO1/p21 axis activation in myoblasts
2020 May; 11(5): 359. Published online 2020 May 12. doi: 10.1038/s41419-020-2552-7Read more
Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation
PMC 2020 Sep 15; 147(6): 1528–1534.
Immunohistochemical detection of senescence markers in human sarcomas
- PMID: 31899047
- DOI: 10.1016/j.prp.2019.152800
Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage
2020; 11: 42. Published online 2020 Jan 2. doi: 10.1038/s41467-019-13894-9
Unique Spatial Immune Profiling in Pancreatic Ductal Adenocarcinoma with Enrichment of Exhausted and Senescent T Cells and Diffused CD47-SIRPα Expression
MDPI Cancers (Basel). 2020;12(7):1825. Published 2020 Jul 7. doi:10.3390/cancers12071825
Cellular Senescence: Defining a Path Forward
Cell Oct 31 2019;179(4):813-827.
Immunohisto(cyto)chemistry: an old time classic tool driving modern oncological therapies
Histol Histopathol. 2019 Apr;34(4):335-352.
Robust, universal biomarker assay to detect senescent cells in biological specimens
Aging Cell. 2017 Feb;16(1):192-197.
Detecting senescence: a new method for an old pigment
Aging Cell (2017)16, pp432–434.
A novel Sudan Black B-based analogue revives lipofuscin as a biomarker for in vivo senescence
Virchows Archiv December 2018, Volume 473, Issue 6, pp 781–783 doi: 10.1007/s00428-018-2452-8
Tracking senescent cells: A new biomarker assay opens new avenues in senescence research
Mech Ageing Dev. 2017 Mar;162:106-107. doi: 10.1016/j.mad.2017.01.009. Epub 2017 Feb 1.
A prototypical non-malignant epithelial mode; to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence
BMC Genomics. 2018 Jan 10;19(1):37
Senescence and senotherapeutics: a new field in cancer therapy
Pharmacol Ther. 2019 Jan;193:31-49.
Ageing, Cellular Senescence and Neurodegenerative Disease
Int J Mol Sci. 2018 Sep 27;19(10)
Sasaki M, Sato Y, Nakanuma Y. An impaired biliary bicarbonate umbrella may be involved in dysregulated autophagy in primary biliary cholangitis
Lab Invest. 2018 Jun;98(6):745-754.
Integrating the DNA damage and protein stress responses during cancer development and treatment
J Pathol. 2018 Sep;246(1):12-40. doi: 10.1002/path.5097
The innate immune sensor Toll like receptor 2 controls the senescence-associated secretory phenotype
Sci. Adv. 2019; 5 : eaaw0254.
In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution
Mech Ageing Dev. 2019 Jan;177:88-90.
An early‐senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a pro‐inflammatory program
Aging Cell. 2019;e12933.
Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells
Nucleic Acids Research, 2019, Vol. 47, No. 6